10.1371/journal.pone.0001977.g002 Jeremy L. Peirce Jeremy L. Peirce Karl W. Broman Karl W. Broman Lu Lu Lu Lu Elissa J. Chesler Elissa J. Chesler Guomin Zhou Guomin Zhou David C. Airey David C. Airey Amanda E. Birmingham Amanda E. Birmingham Robert W. Williams Robert W. Williams The GRAIP approach. Public Library of Science 2013 graip 2013-02-21 10:32:14 Figure https://plos.figshare.com/articles/figure/_The_GRAIP_approach_/602652 <p>This cartoon summarizes the GRAIP approach. First (1) parental happlotypes are regenerated if they are not already known and (2) the parents are permuted. Next (3) the population of offspring is regenerated using the permuted genotypes and (4) permuted maps are generated using the non-permuted phenotypes. Finally, (5) the significance of the permuted maps are compared at a pointwise and whole genome basis with the original map.</p>