10.1371/journal.ppat.1000104.g005
Xiaohong Gao
Xiaohong
Gao
Kim Pin Yeo
Kim
Pin Yeo
Siqi Sharon Aw
Siqi
Sharon Aw
Claudia Kuss
Claudia
Kuss
Jayasree K. Iyer
Jayasree
K. Iyer
Saraswathy Genesan
Saraswathy
Genesan
Ravikumar Rajamanonmani
Ravikumar
Rajamanonmani
Julien Lescar
Julien
Lescar
Zbynek Bozdech
Zbynek
Bozdech
Peter R. Preiser
Peter
R. Preiser
Merozoite invasion properties of <i>P. falciparum</i> W2mef, FCR3, Dd2, 3D7 and HB3 clones.
Public Library of Science
2008
3d7
hb3
2008-07-11 02:08:17
Figure
https://plos.figshare.com/articles/figure/_Merozoite_invasion_properties_of_P_falciparum_W2mef_FCR3_Dd2_3D7_and_HB3_clones_/597697
<p>(A) Comparison of merozoite invasion inhibition with αrRII-3 and αrtRVIII, including pre-immune serum in 1∶10 and 1∶640 dilutions. Positive control was the invasion of merozoites into the normal complete medium. The error bar denotes the SE. * <i>p</i><0.001, indicating that the invasion of W2mef, FCR3 and Dd2 were successfully inhibited by αrRII-3, compared to 3D7 and HB3. + <i>p</i><0.05 indicating that Dd2 exhibit an intermediate sensitivity to inhibitory antiserum as compared to W2mef and FCR3. (B) Parasites were also assayed for their ability to invade neuraminidase-treated erythrocytes (1mU/ml final). For each parasite clone, the percentage of inhibition of the ability to invade neuraminidase-treated erythrocytes (vertical axis) is plotted against the percentage of invasion inhibition of αrRII-3 in a 1∶10 dilution (horizonal axis). Western blot of enriched culture supernatant from all 5 clones used in this study and probed with αrRII-3, αrtRVIII and αSERA5 was shown in the insert of (B). No RH1 protein was detected in 3D7 and HB3 clones compared with W2mef, Dd2 and FCR3.</p>