Workflow and results for Mixed Model analysis of HNE dataset. Lily Wang Bing Zhang Russell D. Wolfinger Xi Chen 10.1371/journal.pgen.1000115.g003 https://plos.figshare.com/articles/figure/_Workflow_and_results_for_Mixed_Model_analysis_of_HNE_dataset_/597696 <p>When individual tests were conducted with 6 hr treatment samples and 24 hr samples separately, only 5 and 1 gene-sets were significant at 0.01 FDR level. However, when all samples were used, for testing gene-sets with non-significant DurationĂ—Linear Trend interaction, 40 gene-sets were significant at 0.01 FDR level. This shows pooling data with similar trends from both treatment durations improves the statistical power for identifying biologically meaningful gene sets.</p> 2008-07-04 02:08:16 hne