J. Hastings, P. Ira, Grzegorz R. Lupski, James In silico analyses revealed complex genomic architecture in regions of nonrecurrent rearrangement. <p>(A) The ∼3 Mb surrounding the <i>PLP1</i> gene and (B) the ∼4 Mb surrounding the <i>MECP2</i> gene on the X chromosome contain numerous LCRs in various orientations <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1000327#pgen.1000327-Lee3" target="_blank">[33]</a>,<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1000327#pgen.1000327-Lee6" target="_blank">[106]</a>. LCRs are represented by the colored block arrows, and like LCR copies are designated by color and letter for a given sequence. Orientation is depicted by the direction of the block arrow.</p> silico;analyses;revealed;genomic;regions;nonrecurrent 2013-02-21
    https://plos.figshare.com/articles/figure/_In_silico_analyses_revealed_complex_genomic_architecture_in_regions_of_nonrecurrent_rearrangement_/581733
10.1371/journal.pgen.1000327.g001