A model for Tup1-mediated regulation of cell fate at the <i>WOR1</i> promoter. AlkafeefSelma S. YuClinton HuangLan LiuHaoping 2018 <p>Tup1 associates at the <i>WOR1</i> promoter and represses <i>WOR1</i> expression. In opaque cells, Wor1 binds along the <i>WOR1</i> promoter and inhibits Tup1-mediated repression of <i>WOR1</i> expression. The effect of temperature and carbon source on Wor1 and Tup1 occupancy at the <i>WOR1</i> promoter is shown. Dark blue or yellow indicates high levels of Wor1 and Tup1, while light colors depict decreased Wor1 or Tup1 at the promoter. Grey circles depict several other well-characterized phase regulators. Grey lines indicate reduced or lost activity.</p>