Hierarchal clustering of differentially expressed genes between HDM-treated C57BL/6<sup><i>Mthfr</i>-/-</sup> and HDM-treated C57BL/6. Kenneth R. Eyring Brent S. Pedersen Kenneth N. Maclean Sally P. Stabler Ivana V. Yang David A. Schwartz 10.1371/journal.pone.0190916.g003 https://plos.figshare.com/articles/figure/Hierarchal_clustering_of_differentially_expressed_genes_between_HDM-treated_C57BL_6_sup_i_Mthfr_i_-_-_sup_and_HDM-treated_C57BL_6_/5784690 <p>ANOVA analysis identified 2,588 transcripts that are differentially expressed between the four experimental groups. Gene clustering by similarity in expression as quantified by the Pearson correlation using average linkage hierarchical clustering show groups of genes related to <i>Mthfr</i> status as well as treatment dependent clusters.</p> 2018-01-12 18:32:38 airway disease WLL Methods Allergic airway disease Mthfr AHR HDM-treated C 57BL mice lung tissue C 57BL airway disease phenotype methyl donors house dust mite airway disease Rationale Environmental exposures carbon metabolite levels