Hierarchal clustering of differentially expressed genes between HDM-treated C57BL/6<sup><i>Mthfr</i>-/-</sup> and HDM-treated C57BL/6.
Kenneth R. Eyring
Brent S. Pedersen
Kenneth N. Maclean
Sally P. Stabler
Ivana V. Yang
David A. Schwartz
10.1371/journal.pone.0190916.g003
https://plos.figshare.com/articles/figure/Hierarchal_clustering_of_differentially_expressed_genes_between_HDM-treated_C57BL_6_sup_i_Mthfr_i_-_-_sup_and_HDM-treated_C57BL_6_/5784690
<p>ANOVA analysis identified 2,588 transcripts that are differentially expressed between the four experimental groups. Gene clustering by similarity in expression as quantified by the Pearson correlation using average linkage hierarchical clustering show groups of genes related to <i>Mthfr</i> status as well as treatment dependent clusters.</p>
2018-01-12 18:32:38
airway disease
WLL
Methods Allergic airway disease
Mthfr
AHR
HDM-treated C 57BL mice
lung tissue
C 57BL
airway disease phenotype
methyl donors
house dust mite
airway disease Rationale Environmental exposures
carbon metabolite levels