%0 Figure %A Matondo, Ramadhan B. %A Moreno, Eva %A J. M. Toussaint, Mathilda %A Tooten, Peter C. J. %A van Essen, Saskia C. %A van Liere, Elsbeth A. %A A. Youssef, Sameh %A Bongiovanni, Laura %A de Bruin, Alain %D 2018 %T Response to energy stress in E2f7/8-deficient pancreas. %U https://plos.figshare.com/articles/figure/Response_to_energy_stress_in_i_E2f7_8-_i_deficient_pancreas_/5784663 %R 10.1371/journal.pone.0190899.g004 %2 https://plos.figshare.com/ndownloader/files/10211466 %K pancreatic polyploid cells %K polyploid cells increases %K E 2fs %K E 2f %K E 2f activity %K polyploidization %K E 2f transcription factors %K Atypical E 2f functions %K blood serum levels %K 4 hours starvation condition %X

(A) Immunostaining for insulin and glucagon under fed conditions in mice injected with tamoxifen at the age of 1 week and analysed at the age of 22 weeks. (B) Immunostaining of insulin and glucagon after 4hrs of starvation. (C-F) Serum biochemical parameters under normal feeding conditions. (G-J) Serum biochemical parameters following 4hrs of starvation. Bar graphs represents average and standard error, *p<0.05.

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