10.1371/journal.pone.0189586.g011
Maëlle Lorvellec
Maëlle
Lorvellec
Federico Scottoni
Federico
Scottoni
Claire Crowley
Claire
Crowley
Rebeca Fiadeiro
Rebeca
Fiadeiro
Panagiotis Maghsoudlou
Panagiotis
Maghsoudlou
Alessandro Filippo Pellegata
Alessandro Filippo
Pellegata
Francesca Mazzacuva
Francesca
Mazzacuva
Asllan Gjinovci
Asllan
Gjinovci
Anne-Marie Lyne
Anne-Marie
Lyne
Justine Zulini
Justine
Zulini
Daniel Little
Daniel
Little
Olukunbi Mosaku
Olukunbi
Mosaku
Deirdre Kelly
Deirdre
Kelly
Paolo De Coppi
Paolo
De Coppi
Paul Gissen
Paul
Gissen
ASGPR expression by hiPSC- or hESC-derived hepatocytes in 2D or 3D on day 13 of differentiation.
Public Library of Science
2017
hepatocyte marker albumin
2 D cultures
hepatocyte marker alpha-fetoprotein
2 D conditions
hepatocyte-like cells Liver transplantation
regenerative medicine applications
Pluripotent Stem Cells
cell hepatocyte differentiation
3 D culture
organ regeneration therapies
optimised 3 D protocols
blood vessel network
mouse decellularised liver scaffold
3 D
donor organ shortage limits
hepatocyte differentiation
hiPSC
2017-12-20 18:38:46
Figure
https://plos.figshare.com/articles/figure/ASGPR_expression_by_hiPSC-_or_hESC-derived_hepatocytes_in_2D_or_3D_on_day_13_of_differentiation_/5724601
<p>(a-b) Immunostaining of hepatocyte sinusoidal membrane protein ASGPR in 2D (a) and 3D (b) cultured cells. Nuclei stained with DAPI. The higher magnification images of merged channels in the bottom panel correspond to the delineated lower magnification images in the panel above. Images of 3D cultured cells demonstrate membrane localisation of ASGPR.</p>