%0 Figure %A Battaglia, Giuseppe %A Molinaro, Gemma %A Riozzi, Barbara %A Storto, Marianna %A L. Busceti, Carla %A Spinsanti, Paola %A Bucci, Domenico %A Di Liberto, Valentina %A Mudò, Giuseppina %A Corti, Corrado %A Corsi, Mauro %A Nicoletti, Ferdinando %A Belluardo, Natale %A Bruno, Valeria %D 2013 %T In situ hybridization of sagittal sections at basal ganglia level showing the expression of mRNA encoding GDNF (A) or NGF (B). %U https://plos.figshare.com/articles/figure/_In_situ_hybridization_of_sagittal_sections_at_basal____ganglia_level_showing_the_expression_of_mRNA_encoding_GDNF_A_or_NGF____B_/558004 %R 10.1371/journal.pone.0006591.g001 %2 https://plos.figshare.com/ndownloader/files/887581 %K hybridization %K sagittal %K sections %K basal %K ganglia %K mrna %K encoding %K gdnf %K ngf %X

Autoradiogram showing GDNF expression in the striatum of saline-treated mice or LY379268 (0.25 mg/kg, i.p.)-treated mice (A). The inserts show representative GDNF mRNA labeled cells (black grains) with increased levels of labeling in LY379268-treated mice. Autoradiogram showing NGF expression of saline-treated mice or LY379268 (0.25 mg/kg, i.p.)-treated mice (B). Dose-response curve of GDNF mRNA levels in the striatum of mice treated with saline or LY379268 (0.1, 0.25, 1, 3 or 4 mg/kg, i.p) (C) and time-course of GDNF mRNA levels in the striatum of mice after a single injection of LY379268 (0.25 mg/kg, i.p.) (D); values are means±S.E.M (n = 4–5, animals per group; three independent experiments). Striatal GDNF mRNA levels in mice treated with saline, LY379268 (0.25 mg/kg, i.p), LY341495 (1 mg/kg, i.p) or LY379268+LY341495 (E); value are means±S.E.M (n = 4, animals per group; three independent experiments). *p<0.05; **p<0.01 (One-way ANOVA+Fisher's PLSD) vs. control mice. Scale bar: A–B = 4 mm. Str, striatum; Ctx, cortex; Hipp, hippocampus.

%I PLOS ONE