10.1371/journal.pone.0186387.g001 Leonard Bergau Leonard Bergau Tobias Tichelbäcker Tobias Tichelbäcker Barbora Kessel Barbora Kessel Lars Lüthje Lars Lüthje Thomas H. Fischer Thomas H. Fischer Tim Friede Tim Friede Markus Zabel Markus Zabel Flow chart showing the results of the literature search and the number of available studies regarding the chosen end-points and the considered factors. Public Library of Science 2017 LIVIVO risk factors mortality 2016. Study selection Studies prophylactic ICD therapy LVEF ischemic cardiomyopathy HR ICD shock therapy CI CENTRAL data source PubMed ICM 2017-10-17 17:39:35 Figure https://plos.figshare.com/articles/figure/Flow_chart_showing_the_results_of_the_literature_search_and_the_number_of_available_studies_regarding_the_chosen_end-points_and_the_considered_factors_/5507194 <p>HR stands for hazard ratio and PP for primary prevention.</p>