%0 Figure %A Karandrea, Shpetim %A Yin, Huquan %A Liang, Xiaomei %A L. Slitt, Angela %A Heart, Emma A. %D 2017 %T Effects of TQ on NADH/NAD+ ratio in liver and soleus muscle. %U https://plos.figshare.com/articles/figure/Effects_of_TQ_on_NADH_NAD_sup_sup_ratio_in_liver_and_soleus_muscle_/5444821 %R 10.1371/journal.pone.0185374.g006 %2 https://plos.figshare.com/ndownloader/files/9412921 %K NAD %K activation %K serum cholesterol levels %K insulin tolerance tests %K insulin sensitivity %K phosphorylated SIRT %K SIRT -1-dependent pathways Thymoquinone %K OGTT %K plant Nigella sativa %K ameliorate %K AMPK %K type 2 diabetes %K NADH %K SIRT -1-dependent pathways %K fasting blood glucose %K insulin-resistant HepG 2 cells %K SIRT -1-dependent mechanism %K DIO mouse model %K ITT %K fasting insulin levels %K TQ %K phenotype %K intracellular redox cycling %K Diet-Induced Obesity mice %K MCP %X

(A) NADH/NAD+ ratio in liver. (B) NADH/NAD+ ratio in soleus muscle. p ≤ 0.05 when comparing (+) HFD and LFD, (*) HFD + TQ and HFD, and (#) LFD and LFD + TQ using independent t-tests. Results are means ± SEM (n = 8–10 mice per treatment group). LFD: low fat diet, HFD: high fat diet, TQ: thymoquinone.

%I PLOS ONE