Effects of TQ on NADH/NAD<sup>+</sup> ratio in liver and soleus muscle.
Shpetim Karandrea
Huquan Yin
Xiaomei Liang
Angela L. Slitt
Emma A. Heart
10.1371/journal.pone.0185374.g006
https://plos.figshare.com/articles/figure/Effects_of_TQ_on_NADH_NAD_sup_sup_ratio_in_liver_and_soleus_muscle_/5444821
<p>(A) NADH/NAD<sup>+</sup> ratio in liver. (B) NADH/NAD<sup>+</sup> ratio in soleus muscle. p ≤ 0.05 when comparing (+) HFD and LFD, (*) HFD + TQ and HFD, and (#) LFD and LFD + TQ using independent t-tests. Results are means ± SEM (n = 8–10 mice per treatment group). LFD: low fat diet, HFD: high fat diet, TQ: thymoquinone.</p>
2017-09-26 17:35:44
NAD
activation
serum cholesterol levels
insulin tolerance tests
insulin sensitivity
phosphorylated SIRT
SIRT -1-dependent pathways Thymoquinone
OGTT
plant Nigella sativa
ameliorate
AMPK
type 2 diabetes
NADH
SIRT -1-dependent pathways
fasting blood glucose
insulin-resistant HepG 2 cells
SIRT -1-dependent mechanism
DIO mouse model
ITT
fasting insulin levels
TQ
phenotype
intracellular redox cycling
Diet-Induced Obesity mice
MCP