Effects of TQ on NADH/NAD<sup>+</sup> ratio in liver and soleus muscle. Shpetim Karandrea Huquan Yin Xiaomei Liang Angela L. Slitt Emma A. Heart 10.1371/journal.pone.0185374.g006 https://plos.figshare.com/articles/figure/Effects_of_TQ_on_NADH_NAD_sup_sup_ratio_in_liver_and_soleus_muscle_/5444821 <p>(A) NADH/NAD<sup>+</sup> ratio in liver. (B) NADH/NAD<sup>+</sup> ratio in soleus muscle. p ≤ 0.05 when comparing (+) HFD and LFD, (*) HFD + TQ and HFD, and (#) LFD and LFD + TQ using independent t-tests. Results are means ± SEM (n = 8–10 mice per treatment group). LFD: low fat diet, HFD: high fat diet, TQ: thymoquinone.</p> 2017-09-26 17:35:44 NAD activation serum cholesterol levels insulin tolerance tests insulin sensitivity phosphorylated SIRT SIRT -1-dependent pathways Thymoquinone OGTT plant Nigella sativa ameliorate AMPK type 2 diabetes NADH SIRT -1-dependent pathways fasting blood glucose insulin-resistant HepG 2 cells SIRT -1-dependent mechanism DIO mouse model ITT fasting insulin levels TQ phenotype intracellular redox cycling Diet-Induced Obesity mice MCP