10.1371/journal.pone.0183855.g002
A. M. T. Schmitz
A. M. T.
Schmitz
W. B. Veldhuis
W. B.
Veldhuis
M. B. E. Menke-Pluijmers
M. B. E.
Menke-Pluijmers
W. J. M. van der Kemp
W. J. M.
van der Kemp
T. A. van der Velden
T. A.
van der Velden
M. A. Viergever
M. A.
Viergever
W. P. T. M. Mali
W. P. T. M.
Mali
M. C. J. M. Kock
M. C. J. M.
Kock
P. J. Westenend
P. J.
Westenend
D. W. J. Klomp
D. W. J.
Klomp
K. G. A. Gilhuijs
K. G. A.
Gilhuijs
Examples of 7 tesla MR imaging in three patients, showing the first post-contrast dynamic contrast-enhanced MR imaging in the (A) transverse plane and the (B) coronal plane, with (C) the corresponding apparent diffusion coefficient (ADC) map; and (D) the corresponding 31-phosphorus MR spectroscopy (<sup>31</sup>P-MRS) scoring upon the ratio of phosphomonoesters (PME) to phosphodiesters (PDE).
Public Library of Science
2017
decision model
DCE
10- year risk-estimates
31- phosphorus spectroscopy
therapy
preoperative indication
tumor size
preoperative decision model
breast cancer mortality
31 P-MRS
Preoperative indication
7- tesla field strength
multiparametric 7- tesla breast MRI Purpose
early-stage breast cancer
PME
postoperative indication
DCE-MRI
31 P-MRS score
preoperative multiparametric 7- tesla breast MRI
2017-09-26 17:25:49
Figure
https://plos.figshare.com/articles/figure/Examples_of_7_tesla_MR_imaging_in_three_patients_showing_the_first_post-contrast_dynamic_contrast-enhanced_MR_imaging_in_the_A_transverse_plane_and_the_B_coronal_plane_with_C_the_corresponding_apparent_diffusion_coefficient_ADC_map_and_D_the_corresponding/5443810
<p>All three patients (left/middle/right) had a negative preoperative indication for systemic therapy based on biopsy and conventional breast imaging. On <u>the left</u>, imaging is shown of a 47-year old woman. The decision-tree model upstages this assessment to positive indication: DCE-MRI showed a 23-mm sized lesion, an ADC of 746 x10<sup>−6</sup>mm<sup>2</sup>/s, and a PME>PDE score. Postoperatively, a grade 2 tumor and a positive indication for systemic therapy was established. <u>In the middle</u>, imaging is shown of a 58-year old women. The decision-tree model again upstages this assessment to positive indication: DCE-MRI showed an 18-mm sized lesion, an ADC of 980 x10<sup>−6</sup>mm<sup>2</sup>/s. The MRS score was, however, PME>PDE. Postoperatively, a grade 2 tumor and a positive indication for systemic therapy was established. <u>On the right</u>, imaging is shown of a 71-year old woman. The decision-tree model confirms the negative indication: DCE-MRI showed a 16-mm sized lesion, DWI a mean ADC of 834 x10<sup>−6</sup>mm<sup>2</sup>/s, and <sup>31</sup>P-MRS a PME</p>