%0 Figure %A Park, Siwan %A Jang, Hwanseok %A Kim, Byung Soo %A Hwang, Changmo %A Jeong, Gi Seok %A Park, Yongdoo %D 2017 %T Illustration of extravasation and directional migration of MSCs in different conditions. %U https://plos.figshare.com/articles/figure/Illustration_of_extravasation_and_directional_migration_of_MSCs_in_different_conditions_/5392699 %R 10.1371/journal.pone.0184595.g008 %2 https://plos.figshare.com/ndownloader/files/9284437 %K migration %K plasma membrane receptor CXCR 4 %K MSC %K stromal cell-derived factor 1 %K pathway %K EC %K CXCR 4 antagonist AMD 3100 %K microfluidic device %K microfluidic device Homing %K SDF %X

(a) Morphology of a normal MSC. (b) An MSC under SDF-1α gradient. (c) An MSC exposed to Y-27632, a Rho-ROCK inhibitor. (d) An MSC exposed to AMD3100, a CXCR4 antagonist. (e) MSC exposed to NSC23766, a Rac inhibitor. (f) Migration of MSCs due to the chemokine effect of SDF-1α. Blue color represents the number of stem cells migrating in response to the homing factor.

%I PLOS ONE