10.1371/journal.pone.0184595.g008 Siwan Park Siwan Park Hwanseok Jang Hwanseok Jang Byung Soo Kim Byung Soo Kim Changmo Hwang Changmo Hwang Gi Seok Jeong Gi Seok Jeong Yongdoo Park Yongdoo Park Illustration of extravasation and directional migration of MSCs in different conditions. Public Library of Science 2017 migration plasma membrane receptor CXCR 4 MSC stromal cell-derived factor 1 pathway EC CXCR 4 antagonist AMD 3100 microfluidic device microfluidic device Homing SDF 2017-09-08 18:15:05 Figure https://plos.figshare.com/articles/figure/Illustration_of_extravasation_and_directional_migration_of_MSCs_in_different_conditions_/5392699 <p>(a) Morphology of a normal MSC. (b) An MSC under SDF-1α gradient. (c) An MSC exposed to Y-27632, a Rho-ROCK inhibitor. (d) An MSC exposed to AMD3100, a CXCR4 antagonist. (e) MSC exposed to NSC23766, a Rac inhibitor. (f) Migration of MSCs due to the chemokine effect of SDF-1α. Blue color represents the number of stem cells migrating in response to the homing factor.</p>