10.1371/journal.pone.0184595.g008
Siwan Park
Siwan
Park
Hwanseok Jang
Hwanseok
Jang
Byung Soo Kim
Byung Soo
Kim
Changmo Hwang
Changmo
Hwang
Gi Seok Jeong
Gi Seok
Jeong
Yongdoo Park
Yongdoo
Park
Illustration of extravasation and directional migration of MSCs in different conditions.
Public Library of Science
2017
migration
plasma membrane receptor CXCR 4
MSC
stromal cell-derived factor 1
pathway
EC
CXCR 4 antagonist AMD 3100
microfluidic device
microfluidic device Homing
SDF
2017-09-08 18:15:05
Figure
https://plos.figshare.com/articles/figure/Illustration_of_extravasation_and_directional_migration_of_MSCs_in_different_conditions_/5392699
<p>(a) Morphology of a normal MSC. (b) An MSC under SDF-1α gradient. (c) An MSC exposed to Y-27632, a Rho-ROCK inhibitor. (d) An MSC exposed to AMD3100, a CXCR4 antagonist. (e) MSC exposed to NSC23766, a Rac inhibitor. (f) Migration of MSCs due to the chemokine effect of SDF-1α. Blue color represents the number of stem cells migrating in response to the homing factor.</p>