10.1371/journal.ppat.1006562.g002 Elad Milrot Elad Milrot Eyal Shimoni Eyal Shimoni Tali Dadosh Tali Dadosh Katya Rechav Katya Rechav Tamar Unger Tamar Unger James L. Van Etten James L. Van Etten Abraham Minsky Abraham Minsky PBCV-1 infected chlorella cells at 2 min PI. Public Library of Science 2017 host photosynthetic membranes genome internalization genome internalization process infection stages PBCV host cell wall eukaryotic-like infection pathway infection stages dsDNA Paramecium bursaria chlorella virus eukaryote-infecting Paramecium bursaria chlorella virus bacteriophage-like replication cycle 2017-08-29 17:43:10 Figure https://plos.figshare.com/articles/figure/PBCV-1_infected_chlorella_cells_at_2_min_PI_/5355865 <p>A, C. TEM micrographs highlighting the hurdles that are associated with trafficking large viral DNA genomes to the nucleus. The large chloroplast is visible with an adjacent virus attached. The nucleus is located at the opposite side of the cell. B, D. High magnifications of panels A and C, respectively, showing the tightly packed thylakoid membrane (red arrowheads) and PBCV-1 virions attached adjacent to the thylakoid membrane stacks. Note that Panel D is rotated by 90o counter clockwise relative to Panel C. Scale bars: A, C: 500 nm; B, D: 100 nm.</p>