Rode, Sandra Ohm, Henrike Zipfel, Jaqueline Rumpf, Sebastian Mfap1 can be found in a complex with TDP-43. <p>The indicated GFP-tagged Mfap1 constructs (or GFP only as a control) were cotransfected with HA-tagged TDP-43 plasmids into S2 cells and immunoprecipitated with antibodies against GFP. Precipitates were analysed by Western blotting with GFP antibodies to detect GFP fusion proteins, or HA antibodies to detect coprecipitated <sup>HA</sup>TDP-43. (A) Coimmunoprecipitation of <sup>HA</sup>TDP-43 with Mfap1-GFP.(B) Coimmunoprecipitations of <sup>HA</sup>TDP-43 with GFP-Mfap1<sup>1-229</sup> or GFP-Mfap1<sup>230-478</sup>. (C) Coimmunoprecipitation of <sup>HA</sup>TDP-43 lacking the glycine-rich region (<sup>HA</sup>TDP-43 Δgly) with Mfap1-GFP. For better comparison, these lanes are from the same blot and exposure as the experiment in (A). (D) Schematic summary of Mfap1 domain interactions. GFP bands in Mfap1-GFP samples are likely due to partial proteolysis after lysis.</p> c 4da neurons;disease-associated RNA-binding protein;TDP;Drosophila class IV dendritic arborization;RNA binding proteins;Mfap 1 function;AAA chaperone Valosin-Containing Protein;VCP binding region;Mfap 1 overexpression causes c 4da neuron dendrite;Drosophila Posttranscriptional regulation;Mfap 1;spliceosome-associated protein Mfap 1 2017-08-24
    https://plos.figshare.com/articles/figure/Mfap1_can_be_found_in_a_complex_with_TDP-43_/5342356
10.1371/journal.pone.0183733.g005