Effect of a 5-day treatment with morusin (in mg/kg) on (A) interleukin 1β, (B) transforming growth factor β1, (C) superoxide dismutase and (D) catalase levels in TNBS-induced colitis, compared to the intact group, the untreated group (CTRL), and the group treated with sulfasalazine 50 mg/kg (SAS). Zora Vochyánová Marie Pokorná Dominik Rotrekl Václav Smékal Petr Fictum Pavel Suchý Jan Gajdziok Karel Šmejkal Jan Hošek 10.1371/journal.pone.0182464.g004 https://plos.figshare.com/articles/figure/Effect_of_a_5-day_treatment_with_morusin_in_mg_kg_on_A_interleukin_1_B_transforming_growth_factor_1_C_superoxide_dismutase_and_D_catalase_levels_in_TNBS-induced_colitis_compared_to_the_intact_group_the_untreated_group_CTRL_and_the_group_treated_with_sulfa/5300710 <p>Values were obtained from Western blot analysis, quantified by densitometry, and normalized to the β-actin level, as described in Materials and methods. Representative blots are shown. The results are expressed as the mean, with error bars representing SEM. CTRL vs. intact group: ## <i>p</i> < 0.01; CTRL vs. treated groups: * <i>p</i> < 0.05, ** <i>p</i> < 0.01, *** <i>p</i> < 0.001.</p> 2017-08-10 18:10:19 MMP 2 superoxide dismutase dose zymographic analysis TGF -β1 levels tissue damage scores root bark Morus alba TNBS-induced colitis rats Morusin growth factor Prenylated flavonoid morusin anti-inflammatory agents mg sulfasalazine Wistar rats SOD IL -1β. Many studies matrix metalloproteinases antioxidant enzymes MMP 9 activities prenylated flavonoid bowel disease