%0 Figure %A D. Eckerle, Lance %A M. Becker, Michelle %A A. Halpin, Rebecca %A Li, Kelvin %A Venter, Eli %A Lu, Xiaotao %A Scherbakova, Sana %A L. Graham, Rachel %A S. Baric, Ralph %A B. Stockwell, Timothy %A J. Spiro, David %A R. Denison, Mark %D 2010 %T Mutation counts and rates in viral clones. %U https://plos.figshare.com/articles/figure/_Mutation_counts_and_rates_in_viral_clones_/521581 %R 10.1371/journal.ppat.1000896.g004 %2 https://plos.figshare.com/ndownloader/files/851135 %K counts %K rates %K viral %X

Complete genome sequences were determined for 10 SARS-WT and 10 S-ExoN1 P3 viral clones. Numbers of total (A) or unique (B) non-engineered nucleotide substitutions identified in SARS-WT and S-ExoN1 genomes are indicated. Each circle represents the mutation count value from a single genome sequence and lines indicate mean mutation counts. Rates of accumulation of unique substitutions per replication cycle on a per nucleotide (C) or per genome (D) basis. Mean values are plotted and error bars indicate standard deviations. *, P<0.0005; Wilcoxon rank-sum test.

%I PLOS Pathogens