%0 Figure %A Chang, Ching-Chih %A Lee, Wen-Shin %A Hsieh, Hsian-Guey %A Chuang, Chiao-Lin %A Huang, Hui-Chun %A Lee, Fa-Yauh %A Lee, Shou-Dong %D 2017 %T Pulmonary protein expressions of COX-1, COX-2, NFκB and IκBα. %U https://plos.figshare.com/articles/figure/Pulmonary_protein_expressions_of_COX-1_COX-2_NF_B_and_I_B_/5131372 %R 10.1371/journal.pone.0179809.g005 %2 https://plos.figshare.com/ndownloader/files/8728327 %K cirrhotic rats Objective Hepatopulmonary syndrome %K COX inhibitors %K Results Non-selective COX inhibition %K inhibitor ameliorated HPS %K bile duct ligation %K mortality rate %K COX -2 inhibitor %K inflammation %K NF %K Methods Cirrhotic rats %K Selective cyclooxygenase inhibition %K CBDL %K SC -560 %K non-selective COX inhibitor %K shunt %K hypoxia %X

COX-1 and COX-2 protein expressions were down-regulated by SC-560 and celecoxib treatments (5A). NFκB (p65) and phosphorylated IκBα expressions were also significantly down-regulated by SC-560 and celecoxib treatments (5B).

%I PLOS ONE