10.1371/journal.pone.0178622.g010 Marwan Chami Marwan Chami Ramona Halmer Ramona Halmer Laura Schnoeder Laura Schnoeder Katrin Anne Becker Katrin Anne Becker Carola Meier Carola Meier Klaus Fassbender Klaus Fassbender Erich Gulbins Erich Gulbins Silke Walter Silke Walter Microglial distribution analysis using Iba-1 staining after Asm inhibition by amitriptyline for 2 weeks of recovery period after 5 weeks cuprizone feeding in the CCm. Public Library of Science 2017 amyloid precursor protein oligodendrocyte cell count 12- week cuprizone treatment enzyme acid sphingomyelinase Acid sphingomyelinase deficiency wild-type C 57BL littermates 2 weeks remyelination acid sphingomyelinase demyelination cuprizone animal model 2- week cuprizone withdrawal phase myelin repair study glial reaction sclerosis Detrimental astroglial distribution 2017-06-05 17:34:27 Figure https://plos.figshare.com/articles/figure/Microglial_distribution_analysis_using_Iba-1_staining_after_Asm_inhibition_by_amitriptyline_for_2_weeks_of_recovery_period_after_5_weeks_cuprizone_feeding_in_the_CCm_/5078911 <p>Iba-1<sup>+</sup> cell numbers and iba-1 staining intensity in the CCm of amitriptyline- or control-treated animals showed no significance difference <b>(b, c)</b>.</p>