Volcano plots showing differentially expressed genes following incubation of primary mesothelial cells with <i>S</i>. <i>epidermidis</i> isolates for 1 hour.
Amanda L. McGuire
Kieran T. Mulroney
Christine F. Carson
Ramesh Ram
Grant Morahan
Aron Chakera
10.1371/journal.pone.0178151.g003
https://plos.figshare.com/articles/figure/Volcano_plots_showing_differentially_expressed_genes_following_incubation_of_primary_mesothelial_cells_with_i_S_i_i_epidermidis_i_isolates_for_1_hour_/5037947
<p>Volcano plots showing differentially regulated genes (adj. <i>p</i>-value < 0.05) following exposure of primary mesothelial cells to <i>S</i>. <i>epidermidis</i> ATCC<sup>®</sup> 14990 (A) or <i>S</i>. <i>epidermidis</i> ATCC<sup>®</sup> 12228 (B). A positive Log Fold Change indicates up-regulation; a negative Log Fold Change indicates down-regulation. The Log Odds (B value) is the log of the probability that a gene is differentially expressed. A Log Odds value of 0 corresponds to a 50–50 chance that the gene is differentially expressed.</p>
2017-05-24 17:46:10
mesothelial cell response
PD
mesothelial cells
health care costs
Subsequent qPCR validation
gene
mesothelial cell line Met -5A
3 canonical pathways
35 canonical pathways
TNFR
peritoniti
infection
Staphylococcus epidermidis
1 hour exposure
IL
mesothelial cell responses
-17A