%0 Figure %A Ohno, Yoshinori %A Koizumi, Mitsuhito %A Nakayama, Hironao %A Watanabe, Takao %A Hirooka, Masashi %A Tokumoto, Yoshio %A Kuroda, Taira %A Abe, Masanori %A Fukuda, Shinji %A Higashiyama, Shigeki %A Kumagi, Teru %A Hiasa, Yoichi %D 2017 %T Expression of ANP32B in human HCC tissue. %U https://plos.figshare.com/articles/figure/Expression_of_ANP32B_in_human_HCC_tissue_/4989209 %R 10.1371/journal.pone.0177343.g004 %2 https://plos.figshare.com/ndownloader/files/8406728 %K apoptosis-related proteins %K phosphoprotein 32 family member B %K ANP 32B knockdown %K ANP 32B overexpression %K ANP 32B expression %K pro-apoptotic agent staurosporine %K ANP 32B %K RT-PCR %K UICC %K ABT %K Bcl -2 family %K hepatocellular carcinoma %K ANP 32B modulates %K tissue %K ANP 32B expression plasmids %K HCC cells %K ANP 32B mRNA expression %K Bax expression %K HCC cell lines %X

(A) Immunohistochemical staining of ANP32B in human HCC tissues (T) and non-tumor tissues (NT); the scale bar indicates a length of 50 μm. (B) Western blotting analysis of 3 patients with higher expression of ANP32B in T than in NT (tumor high ANP32B) and 2 patients with lower expression of ANP32B in T than in NT (tumor low ANP32B). (C) Levels of ANP32B mRNA in T and NT were compared individually. (D) Patients were divided into two groups by the T/NT ratio of ANP32B mRNA expression. Red bars represent the tumor low ANP32B group and black bars represent the tumor high ANP32B group. The cutoff value that divided the groups was 1.03.

%I PLOS ONE