10.1371/journal.ppat.1001139.g004
Yasuko Hatta
Yasuko
Hatta
Karen Hershberger
Karen
Hershberger
Kyoko Shinya
Kyoko
Shinya
Sean C. Proll
Sean
C. Proll
Richard R. Dubielzig
Richard
R. Dubielzig
Masato Hatta
Masato
Hatta
Michael G. Katze
Michael
G. Katze
Yoshihiro Kawaoka
Yoshihiro
Kawaoka
M. Suresh
M.
Suresh
Apoptosis of CD8 T cells in mice infected with H5N1 viruses.
Public Library of Science
2010
cd8
cells
mice
infected
h5n1
2010-10-07 01:46:04
Figure
https://plos.figshare.com/articles/figure/_Apoptosis_of_CD8_T_cells_in_mice_infected_with_H5N1_viruses_/496364
<p>A and B, BALB/c mice were infected with 18 PFU of HK483 or HK486. At the indicated days after infection, the percentages of total CD8 T cells (Panel A) and K<sup>d</sup>/NP147-specific CD8 T cells (Panel B) expressing active form of caspase-3 were determined by flow cytometry; cells in the BAL were stained with anti-CD8, K<sup>d</sup>/NP147 pentamers, and anti-active caspase-3. Panel C, C57BL/6 (+/+), Fas-deficient (Fas KO) or BIM-deficient (BIM KO) mice (nā=ā3) were infected with 18 PFU of HK483. On the eighth day after infection, the percentages of total CD8 T cells and of D<sup>b</sup>/PA224-specific CD8 T cells expressing active form of caspase-3 in the BAL were determined as in panels A and B above.</p>