10.1371/journal.pone.0176067.g004 Gemma Navarro Gemma Navarro Eva Martínez-Pinilla Eva Martínez-Pinilla Alejandro Sánchez-Melgar Alejandro Sánchez-Melgar Raquel Ortiz Raquel Ortiz Véronique Noé Véronique Noé Mairena Martín Mairena Martín Carlos Ciudad Carlos Ciudad Rafael Franco Rafael Franco Network analysis using STRING. Public Library of Science 2017 glioma cell line resveratrol plakophilin 4 up-regulation Vamp 2 dynamin 1 mRNA control diet synaptic vesicle transport glia gene expression Atp 2017-04-25 18:27:22 Figure https://plos.figshare.com/articles/figure/Network_analysis_using_STRING_/4909247 <p>The list of differentially expressed genes in neocortex after RSV diet was subjected to Network analysis using the STRING software as described in Methods. Square interaction score was set at medium confidence (0.4; scores range from highest, 0.9, to low, 0.15, confidence). Other selected parameters were: average node degree: 1.12, local clustering coefficient: 0.32 and active interaction sources including: text mining, experiments, databases, co-expression, neighborhood, gene fusion and co-occurrence. Moreover, no restrictions were forced in the number of interactions to show. Overexpressed genes are shown within red rectangles. The colors of the edges represent the different types of protein associations, either from known or predicted interactions: from curated databases (blue), experimentally determined (magenta), text mining (green) and co-expression (black).</p>