10.1371/journal.pone.0176307.g002
Stefanos Aivazidis
Stefanos
Aivazidis
Christina M. Coughlan
Christina M.
Coughlan
Abhishek K. Rauniyar
Abhishek K.
Rauniyar
Hua Jiang
Hua
Jiang
L. Alexander Liggett
L. Alexander
Liggett
Kenneth N. Maclean
Kenneth N.
Maclean
James R. Roede
James R.
Roede
The burden of trisomy 21 disrupts the proteostasis network in Down syndrome - Fig 2
Public Library of Science
2017
chromosome 21. Abnormalities
DS
protein quality control dysfunction
PN
proteostasis network
cell viability
2017-04-21 17:30:06
Figure
https://plos.figshare.com/articles/figure/The_burden_of_trisomy_21_disrupts_the_proteostasis_network_in_Down_syndrome_-_Fig_2/4901564
<p><b>LCLs from DS patients enhanced basal levels of ROS production (A) and expression of ER stress genes (B).</b> Unstimulated DS and CTL LCLs were evaluated for basal superoxide and hydrogen peroxide production using flow cytometry. These unstimulated cells were also assessed for ER stress gene expression using qRT-PCR. N = 3; * P<0.05; ** P<0.01; *** P<0.001; **** P<0.0001.</p>