10.1371/journal.pone.0014182.g005 Farbod Rastegar Farbod Rastegar Jian-Li Gao Jian-Li Gao Deana Shenaq Deana Shenaq Qing Luo Qing Luo Qiong Shi Qiong Shi Stephanie H. Kim Stephanie H. Kim Wei Jiang Wei Jiang Eric R. Wagner Eric R. Wagner Enyi Huang Enyi Huang Yanhong Gao Yanhong Gao Jikun Shen Jikun Shen Ke Yang Ke Yang Bai-Cheng He Bai-Cheng He Liang Chen Liang Chen Guo-Wei Zuo Guo-Wei Zuo Jinyong Luo Jinyong Luo Xiaoji Luo Xiaoji Luo Yang Bi Yang Bi Xing Liu Xing Liu Mi Li Mi Li Ning Hu Ning Hu Linyuan Wang Linyuan Wang Gaurav Luther Gaurav Luther Hue H. Luu Hue H. Luu Rex C. Haydon Rex C. Haydon Tong-Chuan He Tong-Chuan He Effect of LPAATβ on tumor growth in the orthotopic model of osteosarcoma. Public Library of Science 2013 orthotopic 2013-02-20 22:06:54 Figure https://plos.figshare.com/articles/figure/_Effect_of_LPAAT_946_on_tumor_growth_in_the_orthotopic_model_of_osteosarcoma_/486011 <p><b>A</b>. Xenogen IVIS 200 bioluminescence imaging of orthotopic tumor growth. Athymic nude mice were periosteally injected at proximal tibia with 143B cells infected with AdR-LPAATβ, AdRFP, or AdR-siLPAATβ for 15 h (10<sup>6</sup> cells/injection). Animals were subjected to Xenogen imaging at the indicated time points. Representative imaging results at 37 days post injection are shown. <b>B</b>. Quantitative analysis of Xenogen imaging signal intensity (photons/sec/cm<sup>2</sup>/steradian) over the time after injection. <b>C</b>. Tumor growth as determined by tumor volume. The dimensions of injection sites were measured roughly every 3 days during the course of study. Tumor volumes (mm<sup>3</sup>) were calculated as described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0014182#s2" target="_blank">Methods</a>. “*” <i>p-value <0.05</i>, “**” <i>p</i>-<i>value <0.001</i>.</p>