10.1371/journal.pone.0173363.g002 Oleksandr V. Popovych Oleksandr V. Popovych Borys Lysyansky Borys Lysyansky Michael Rosenblum Michael Rosenblum Arkady Pikovsky Arkady Pikovsky Peter A. Tass Peter A. Tass Intrinsic dynamics of the STN neurons Eqs (1)–(3) without stimulation. Public Library of Science 2017 closed-loop brain stimulation High-frequency HF feedback stimulation methods open-loop stimulation protocol brain target areas irrespectively brain stimulation DBS 2017-03-08 18:48:28 Figure https://plos.figshare.com/articles/figure/Intrinsic_dynamics_of_the_STN_neurons_Eqs_1_3_without_stimulation_/4735621 <p>The raster plots (A) and (C) and firing rates (relative number of neurons firing a spike at a given time) in plots (B) and (D) illustrate the STN neuronal activity in a strongly synchronized regime (A), (B) with the coupling <i>g</i><sub>G→S</sub> = 1.7 nS/<i>μ</i>m<sup>2</sup> from GPe to STN and in a weakly synchronized regime (C), (D) with <i>g</i><sub>G→S</sub> = 1.28 nS/<i>μ</i>m<sup>2</sup>. The red solid curves in plots (B) and (D) depict the filtered LFP. Stimulation current <i>I</i><sub>stim</sub> = 0.</p>