Kashiwadani, Hideki Kanmura, Yuichi Kuwaki, Tomoyuki The threshold for nociceptive response measured by calibrated forceps was stable for 5 days. <p>(A) Time courses of the nociceptive response threshold of 6 mice over 5 days. A repeated-measured one-way ANOVA revealed that there was no significant difference among days (F<sub>4,20</sub> = 0.3240, <i>p</i> = 0.8585). (B) The thresholds were replotted as the mean ± SEM for 6 animals for each day.</p> time resolution;von Frey test;measurement;threshold;anti-nociceptive effects;nociception;forcep;short-acting analgesics;5 days;device;pain assays;manipulation techniques;5 minute intervals 2017-02-17
    https://plos.figshare.com/articles/figure/The_threshold_for_nociceptive_response_measured_by_calibrated_forceps_was_stable_for_5_days_/4666729
10.1371/journal.pone.0172461.g003