10.1371/journal.pone.0169565.g012 Adam Junka Adam Junka Patrycja Szymczyk Patrycja Szymczyk Grzegorz Ziółkowski Grzegorz Ziółkowski Ewa Karuga-Kuzniewska Ewa Karuga-Kuzniewska Danuta Smutnicka Danuta Smutnicka Iwona Bil-Lula Iwona Bil-Lula Marzenna Bartoszewicz Marzenna Bartoszewicz Susan Mahabady Susan Mahabady Parish Paymon Sedghizadeh Parish Paymon Sedghizadeh Bad to the Bone: On <i>In Vitro</i> and <i>Ex Vivo</i> Microbial Biofilm Ability to Directly Destroy Colonized Bone Surfaces without Participation of Host Immunity or Osteoclastogenesis - Fig 12 Public Library of Science 2017 ANOVA Scanning electron microscopy host cell destruction osteomyeliti Destroy Colonized Bone Surfaces microcomputed tomography analysis impact biofilm formation pH levels Osteoclastogenesis Bone infections scanning electron microscopy Ex Vivo Microbial Biofilm Ability Direct bone resorption Microbial biofilm pathogens bone destruction 2017-01-11 17:38:49 Figure https://plos.figshare.com/articles/figure/Bad_to_the_Bone_On_i_In_Vitro_i_and_i_Ex_Vivo_i_Microbial_Biofilm_Ability_to_Directly_Destroy_Colonized_Bone_Surfaces_without_Participation_of_Host_Immunity_or_Osteoclastogenesis_-_Fig_12/4545067 <p>The geometry of control bone sample (<b>A,</b> left side of Figure), incubated for 30 days in sterile media and geometry of treated bone sample (<b>B</b>, right side of Figure), which was used as a surface for <i>S</i>. <i>aureus</i> biofilm growth. The green surface represents position points which did not change significantly from day 0 to day 30. The colors from light blue to violet represent points which collapsed during 30 days in comparison to day 0, and colors from orange to red represent points which were higher after 30 days of incubation than the same points in the beginning of experiment (day 0).</p>