Kidney expression of duox1 and sod1 is affected by the ketogenic diet in <i>db/db</i> diabetic mice.
Michal M. Poplawski
Jason W. Mastaitis
Fumiko Isoda
Fabrizio Grosjean
Feng Zheng
Charles V. Mobbs
10.1371/journal.pone.0018604.g004
https://plos.figshare.com/articles/figure/_Kidney_expression_of_duox1_and_sod1_is_affected_by_the_ketogenic_diet_in_db_db_diabetic_mice_/452171
<p>(A) Ketogenic diet induces Sod1 expression and normalizes Duox1 expression in the <i>db/db</i> mice. The transcripts that show consistent patterns across <i>db/db</i> data sets are depicted in the clusterograms from the (B) Oxidative Stress and Antioxidant Defense PCR Array and (C) Stress & Toxicity PCR array from SABiosciences. The clusterograms (heat maps) represent relative expression levels for all samples and selected genes included on the real-time PCR arrays. Data for each gene in (A) was normalized to a panel of housekeeping transcripts and expressed as fold change compared to the WT-Chow group. Data are means ± SE (n = 4 for all groups). *p<0.05 (ANOVA) vs. WT-Chow group (or vs. diabetic-Chow groups as indicated by the horizontal bracket).</p>
2013-02-20 19:02:02
duox1
SOD1
affected
ketogenic
diabetic