Advice modulated the standard BOLD response to rewards. BieleGuido RieskampJörg K. KrugelLea R. HeekerenHauke 2011 <p>(A) Regions showing greater BOLD response to positive than to negative feedback after not following advice. Top left: VMPFC (max. <i>z</i>-score = 3.50, <i>x</i> = −4, <i>y</i> = 50, <i>z</i> = −18); top right: Left VST (max <i>z</i>-score  = 3.73, <i>x</i> = −16, <i>y</i> = 12, <i>z</i> = −10); bottom left: Insular cortex (max <i>z</i>-score  = 3.33, <i>x</i> = 38, <i>y</i> = 8, <i>z</i> = −16). (B) Estimated parameter estimates show that following advice led to an attenuation of the standard reward signal (as identified from trials in which participants did not follow advice) in the VMPFC and the VST.</p>