10.1371/journal.ppat.1002124.g006 Livia Vastag Livia Vastag Emre Koyuncu Emre Koyuncu Sarah L. Grady Sarah L. Grady Thomas E. Shenk Thomas E. Shenk Joshua D. Rabinowitz Joshua D. Rabinowitz Flux to pyrimidine nucleotide synthesis induced by HSV-1 infection. Public Library of Science 2011 pyrimidine nucleotide synthesis induced hsv-1 2011-07-14 02:06:29 Figure https://plos.figshare.com/articles/figure/_Flux_to_pyrimidine_nucleotide_synthesis_induced_by_HSV_1_infection_/427589 <p>(<b>A</b>) Schematic of carbon labeling from glutamine to UTP arising during carbon influx from glutamine to the TCA cycle. Red dots denote <sup>13</sup>C atoms originating from uniformly <sup>13</sup>C-labeled glutamine. (<b>B</b>) Plots show the levels of the labeled form of the indicated metabolites expressed as percent of the total metabolite pool. The labeling arose upon switching HSV-KOS infected or mock treated HFF cells to uniformly <sup>13</sup>C-labeled glutamine media. HCMV infected cells were switched at 48 hpi, HSV-1-infected cells at 12 hpi. The x-axis indicates time post media switch (mean ±2 s.e.; n = 2).</p>