10.1371/journal.pone.0023700.g007
Li Li
Li
Li
Dan Qiao
Dan
Qiao
Xiaoying Fu
Xiaoying
Fu
Suihua Lao
Suihua
Lao
Xianlan Zhang
Xianlan
Zhang
Changyou Wu
Changyou
Wu
CD4<sup>+</sup>CD25<sup>+</sup> cells inhibit the production of Th1 cytokines by sorted CD4<sup>+</sup>CD69<sup>+</sup> T cells.
Public Library of Science
2013
cells
inhibit
th1
cytokines
sorted
2013-02-20 15:31:59
Figure
https://plos.figshare.com/articles/figure/_CD4_CD25_cells_inhibit_the_production_of_Th1_cytokines_by_sorted_CD4_CD69_T_cells_/414198
<p>(A) CD4<sup>+</sup>CD25<sup>+</sup> and CD4<sup>+</sup>CD69<sup>+</sup> cells were sorted from purified CD4<sup>+</sup> T cells. (B) Production of IFN-γ and TNF-α by sorted CD4<sup>+</sup>CD69<sup>+</sup> and CD4<sup>+</sup>CD25<sup>+</sup> cells in the presence of purified CD14<sup>+</sup> T cells following stimulation with P1–P6. (C–E) Sorted CD4<sup>+</sup>CD25<sup>+</sup> and CD4<sup>+</sup>CD69<sup>+</sup> cells were cultured at different ratios and cocultured with purified CD14<sup>+</sup> cells in the presence or absence of P1–P6. The supernatants were collected, and cytokine production was assessed by ELISA. One representative result from three independent experiments with similar results is shown. Significant differences compared with incubation with P1–P6 in the absence of Tregs are indicated (*, not significant;**, P<0.05;***, P<0.001).</p>