10.1371/journal.pone.0023709.g001
Hideaki Oike
Hideaki
Oike
Kanji Nagai
Kanji
Nagai
Tatsunobu Fukushima
Tatsunobu
Fukushima
Norio Ishida
Norio
Ishida
Masuko Kobori
Masuko
Kobori
Single feeding delays phase of liver, but not lung clock.
Public Library of Science
2011
feeding
delays
2011-08-25 00:37:52
Figure
https://plos.figshare.com/articles/figure/_Single_feeding_delays_phase_of_liver_but_not_lung_clock_/412272
<p>After a night-time restricted feeding schedule (ZT12-24) for one week, mice were divided into 4 groups and then delayed feeding was applied as follows. Mice in the 4, 8 and 13 h delayed groups were fed from ZT16, 20, and the next ZT1, respectively. Control mice were fed from ZT12 to ZT24. White and black boxes indicate day and night respectively; gray lines show feeding times (A). Representative circadian profiles of reporter luminescence in explants of livers (B) and lungs (C) isolated from <i>mPer2::Luc</i> knockin mice. Peak times of circadian oscillation between 12 and 36 h in culture are shown for liver (D) and lung (E). Values are shown as means ± SEM (n = 7 for ZT12 and ZT16, and n = 5 for ZT20 and ZT1; *<i>p</i><0.05, ***<i>p</i><0.001; vs. control; Dunnett's test).</p>