10.1371/journal.pone.0023709.g001 Hideaki Oike Hideaki Oike Kanji Nagai Kanji Nagai Tatsunobu Fukushima Tatsunobu Fukushima Norio Ishida Norio Ishida Masuko Kobori Masuko Kobori Single feeding delays phase of liver, but not lung clock. Public Library of Science 2011 feeding delays 2011-08-25 00:37:52 Figure https://plos.figshare.com/articles/figure/_Single_feeding_delays_phase_of_liver_but_not_lung_clock_/412272 <p>After a night-time restricted feeding schedule (ZT12-24) for one week, mice were divided into 4 groups and then delayed feeding was applied as follows. Mice in the 4, 8 and 13 h delayed groups were fed from ZT16, 20, and the next ZT1, respectively. Control mice were fed from ZT12 to ZT24. White and black boxes indicate day and night respectively; gray lines show feeding times (A). Representative circadian profiles of reporter luminescence in explants of livers (B) and lungs (C) isolated from <i>mPer2::Luc</i> knockin mice. Peak times of circadian oscillation between 12 and 36 h in culture are shown for liver (D) and lung (E). Values are shown as means ± SEM (n = 7 for ZT12 and ZT16, and n = 5 for ZT20 and ZT1; *<i>p</i><0.05, ***<i>p</i><0.001; vs. control; Dunnett's test).</p>