10.1371/journal.pone.0025222.g005
Jelena Põlajeva
Jelena
Põlajeva
Anna M. Sjösten
Anna
M. Sjösten
Nina Lager
Nina
Lager
Marianne Kastemar
Marianne
Kastemar
Ida Waern
Ida
Waern
Irina Alafuzoff
Irina
Alafuzoff
Anja Smits
Anja
Smits
Bengt Westermark
Bengt
Westermark
Gunnar Pejler
Gunnar
Pejler
Lene Uhrbom
Lene
Uhrbom
Elena Tchougounova
Elena
Tchougounova
Co-expression of CXCR4 and mMCP-6 by MCs in mouse RCAS-<i>KRas</i>+RCAS-<i>Akt</i> induced gliomas.
Public Library of Science
2013
cxcr4
mmcp-6
mcs
induced
2013-02-20 14:39:50
Figure
https://plos.figshare.com/articles/figure/_Co_expression_of_CXCR4_and_mMCP_6_by_MCs_in_mouse_RCAS_KRas_RCAS_Akt_induced_gliomas_/404685
<p>(<b>A</b>) Immunofluorescence staining for CXCR4 and mMCP-6 was performed in both <i>Ntv-a Arf−/−</i> and <i>Gtv-a Arf−/−</i> mouse gliomas, demonstrating co-expression of CXCR4 and mMCP-6. Scale bar = 50 µM. (<b>B</b>) Immunofluorescence staining, demonstrated co-localization of CXCR4 and mMCP-6 at the single-cell level in both <i>Ntv-a Arf−/−</i> and <i>Gtv-a Arf−/−</i> mouse gliomas. Maximum intensity projection of z-stack confocal images was applied. Scale bar = 20 µM. (<b>C</b>) The quantification of MCs in mouse brain tumors revealed about 90% to be CXCR4-positive in the corresponding objective fields with no difference between <i>Ntv-a Arf−/−</i> (n = 5) and <i>Gtv-a Arf−/−</i> (n = 5). Error bars show SD.</p>