Schematic and crystal structure of cTnC. Myriam A. Badr Jose R. Pinto Michael W. Davidson P. Bryant Chase 10.1371/journal.pone.0164222.g002 https://plos.figshare.com/articles/figure/Schematic_and_crystal_structure_of_cTnC_/4029666 <p>cTnC is shown in a schematic representation (gray, left) and the crystal structure (PDB 1J1E, right). Mutated residues (used in a subset of studies) are: D65 highlighted in orange at the N-terminus; and D104 and D140 highlighted in red and yellow, respectively, at the C-terminus.</p> 2016-10-13 17:30:01 affinity C-terminal EF hands end point titrations divalent cation binding Divalent Cation-Dependent Conformational Changes cTnC sensor Mg divalent cations bind divalent cation-dependent FRET signal skinned fiber preparations divalent cations YFP CTV-TnC Cardiac Troponin C Cardiac troponin C CFP