Thompson, Melanie L. Heath, Sonya Sweeton, Bentley Williams, Kathy Cunningham, Pamela F. Keele, Brandon Sen, Sharon E. Palmer, Brent Chomont, Nicolas Xu, Yongxian Basu, Rahul Hellerstein, Michael S. Kwa, Suefen Robinson, Harriet L. Mapping of Elicited T Cell Responses to 11 Pools of Sequential Gag Peptides. <p>Panel A shows examples of the CD8+ and CD4+ responses in three participants. Panel B summarizes responses for the eight participants that completed the trial. <sup>1</sup>01–3 had a high background at TI allowing only dominant responses to be scored. Pre, responses present before vaccination; PV, responses scored after the 2<sup>nd</sup> MVA inoculation; TI, Responses scored at 2 weeks post the re-emergence of virus during treatment interruption. Red indicates responses present at baseline, post vaccination and either present or absent post TI, yellow indicates responses observed post vaccination and post treatment interruption, blue indicates responses scored only post vaccination and green indicates responses scored only during treatment interruption.</p> 8 weeks;38 years;Gag selection;plasma HIV;control virus;Median age;grade 4 events;Infected Participants;2 MVA;Phase 1 open-label trial;treatment interruption;4 weeks;antiretroviral therapy;8 participants;vaccine-matched Gag peptides;display signs;vaccine-elicited T cell responses;Treatment Interruption;RNA;re-emergence;GOVX-B;6 months;Immune Responses;vaccination;baseline CD 4 count;DNA;GV-TH;antiretroviral treatment;18 months;Antiretroviral Therapy;pre-ART HIV;re-emergent virus;reactogenicity events;Elicited T cells;Viral Suppression;TI;9 participants;NCT;study drug 2016-10-06
    https://plos.figshare.com/articles/figure/Mapping_of_Elicited_T_Cell_Responses_to_11_Pools_of_Sequential_Gag_Peptides_/3998328
10.1371/journal.pone.0163164.g009