10.1371/journal.pone.0162010.g003 Björn Gerdle Björn Gerdle Malin Ernberg Malin Ernberg Kaisa Mannerkorpi Kaisa Mannerkorpi Britt Larsson Britt Larsson Eva Kosek Eva Kosek Nikolaos Christidis Nikolaos Christidis Bijar Ghafouri Bijar Ghafouri Pain intensity (mean ± SEM) before and after the 15-week exercise intervention in FMS (upper panel) and CON (lower panel) at the time points 140 (baseline), 160 (immediately after the 20-min work period), 180 (recovery), 200 (recovery), and 220 (recovery) min. Public Library of Science 2016 algesic muscle alterations pyruvate MD pain intensity exercise intervention vastus lateralis muscle study muscle alterations FMS group Case-Control Study Background Fibromyalgia syndrome Muscle blood flow concentration PPT pressure pain thresholds 15- week exercise intervention 2016-10-03 17:30:01 Figure https://plos.figshare.com/articles/figure/Pain_intensity_mean_SEM_before_and_after_the_15-week_exercise_intervention_in_FMS_upper_panel_and_CON_lower_panel_at_the_time_points_140_baseline_160_immediately_after_the_20-min_work_period_180_recovery_200_recovery_and_220_recovery_min_/3981069 <p>Note the different y-axis. * denotes significant difference in pain intensity at that time point between before and after the exercise intervention.</p>