%0 Figure %A Xin, Zhongshuai %A Han, Wei %A Zhao, Zhiqiang %A Xia, Qing %A Yin, Bin %A Yuan, Jiangang %A Peng, Xiaozhong %D 2011 %T Model of PCBP2-modulating effect of IFN-α against HCV. %U https://plos.figshare.com/articles/figure/_Model_of_PCBP2_modulating_effect_of_IFN_945_against_HCV_/397751 %R 10.1371/journal.pone.0025419.g007 %2 https://plos.figshare.com/ndownloader/files/727397 %K pcbp2-modulating %X

PCBP2 enhances the antiviral activity of IFN-α through stabilizing the mRNA of STAT1 and STAT2. This accordingly, increases the protein level of the two molecules. The protein level increase also enhances the effect of IFN-α against HCV.

%I PLOS ONE