10.1371/journal.pone.0151211.g001
Magdalena Zurek
Magdalena
Zurek
Louise Sladen
Louise
Sladen
Edvin Johansson
Edvin
Johansson
Marita Olsson
Marita
Olsson
Sonya Jackson
Sonya
Jackson
Hui Zhang
Hui
Zhang
Gaell Mayer
Gaell
Mayer
Paul D. Hockings
Paul
D. Hockings
Representative TI = 6000 ms image, lung density (S0<sub>air</sub>), R1<sub>air</sub>, R1<sub>O2</sub> maps of a control and PPE-challenged mouse lung.
Public Library of Science
2016
MRI
lung function
lung density
oxygen delivery
OE-MRI
resonance imaging method
oxygen uptake
region
relaxation time indices
ultrashort echo-time imaging sequence
C 57BL mice
porcine pancreatic elastase
Principal Findings PPE-challenged mice
PPE-challenged animals
2016-03-15 00:25:18
Figure
https://plos.figshare.com/articles/figure/Representative_TI_6000_ms_image_lung_density_S0_sub_air_sub_R1_sub_air_sub_R1_sub_O2_sub_maps_of_a_control_and_PPE-challenged_mouse_lung_/3961278
<p>The maps are overlaid on TI = 6000 ms image acquired when animals were breathing air (a). ΔR1 (oxygen uptake), ΔR2* (oxygen delivery) maps for the same control and a PPE-challenged mouse (b). The challenged mouse exhibits less uniform distributions of ΔR1 and ΔR2* suggesting that the oxygen uptake and delivery to the lung were more heterogeneous. Regions of spatially matched ΔR1 and ΔR2* are indicated by arrows. Mean ΔR1 assessed in 20 bins based on ΔR2* for control (open squares) and PPE-challenged (filled squares) mice, showing excellent correlation between ΔR1 and ΔR2* (c).</p>