%0 Figure %A Tsujikawa, Tetsuya %A Asahi, Satoko %A Oh, Myungmi %A Sato, Yoshitaka %A Narita, Norihiko %A Makino, Akira %A Mori, Tetsuya %A Kiyono, Yasushi %A Tsuchida, Tatsuro %A Kimura, Hirohiko %A Fujieda, Shigeharu %A Okazawa, Hidehiko %D 2016 %T Kaplan-Meier curves of progression-free survival (PFS) for 62Cu-ATSM PET (a) and 18F-FDG PET (b) in patients with HNC. %U https://plos.figshare.com/articles/figure/Kaplan-Meier_curves_of_progression-free_survival_PFS_for_sup_62_sup_Cu-ATSM_PET_a_and_sup_18_sup_F-FDG_PET_b_in_patients_with_HNC_/3939063 %R 10.1371/journal.pone.0155635.g003 %2 https://plos.figshare.com/ndownloader/files/6161577 %K 18 F-FDG %K threshold %K TMR ATSM %K SUV ATSM %K ROC analysis %K RTV %K CSS %K 18 F-FDG PET scans %K PSF %K 62 Cu-ATSM PET %K 18 F-FDG PET %K 62 Cu-ATSM %K Tumor Redox Status %K HNC patient outcomes %K TLR %K TLG %K tumor-to-muscle activity concentration ratios %K 62 Cu-ATSM PET Purpose Tumor redox %K MTV %K II %K PFS %K Conclusion Tumor redox parameters %K pretreatment 62 Cu-ATSM %X

Two groups of high (dotted lines) and low (solid lines) tracer accumulation were determined by each cut-off value of the tumor-to-muscle ratios (TMRATSM and TMRFDG). TMRATSM, one of the intensity-based redox parameters, showed a significant difference in PFS between two groups (p = 0.03), whereas TMRFDG, one of the intensity-based metabolic parameters, did not (p = 0.15). The three-year PFS rate was 74% for patients with lower accumulation tumors (TMRATSM ≤ 3.2) and 29% for those with over-reductive tumors (TMRATSM > 3.2).

%I PLOS ONE