10.1371/journal.pone.0157540.g001 Sol Moe Lee Sol Moe Lee Myungguen Chung Myungguen Chung Jae Wook Hyeon Jae Wook Hyeon Seok Won Jeong Seok Won Jeong Young Ran Ju Young Ran Ju Heebal Kim Heebal Kim Jeongmin Lee Jeongmin Lee SangYun Kim SangYun Kim Seong Soo A. An Seong Soo A. An Sung Beom Cho Sung Beom Cho Yeong Seon Lee Yeong Seon Lee Su Yeon Kim Su Yeon Kim Results of RT-QuIC analysis. Public Library of Science 2016 Other Neurodegenerative Disorders Inherited prion diseases PRNP LPA FGF IPD LRRK prion protein gene V 180I mutation WGS Genetic Creutzfeldt-Jakob Disease Patients ND V 180I Mutation P 102L V 180I gCJD patients 200K variant 2016-06-24 19:25:42 Figure https://plos.figshare.com/articles/figure/Results_of_RT-QuIC_analysis_/3925632 <p>ThT fluorescence was measured by relative fluorescence units (rfu) with saturation occurring at 65,000 for every 42 min. The RT-QuIC responses were performed using 10<sup>−3</sup> dilution of sCJD patient with 129MM type brain homogenate (NHBX0/0001), 10<sup>−5</sup> CJD negative control brain homogenate (NHBZ0/0005), 15ul of 10<sup>−1</sup> dilution of CSF from 4 gCJD cases with V180I (the Patients nos. 1, 2, 3 and 5) and 1 sCJD case with 129MM. Each point represents the mean of 4 replicate rfu readings.</p>