10.1371/journal.pone.0157540.g001
Sol Moe Lee
Sol Moe
Lee
Myungguen Chung
Myungguen
Chung
Jae Wook Hyeon
Jae Wook
Hyeon
Seok Won Jeong
Seok
Won Jeong
Young Ran Ju
Young
Ran Ju
Heebal Kim
Heebal
Kim
Jeongmin Lee
Jeongmin
Lee
SangYun Kim
SangYun
Kim
Seong Soo A. An
Seong
Soo A. An
Sung Beom Cho
Sung Beom
Cho
Yeong Seon Lee
Yeong Seon
Lee
Su Yeon Kim
Su Yeon
Kim
Results of RT-QuIC analysis.
Public Library of Science
2016
Other Neurodegenerative Disorders Inherited prion diseases
PRNP
LPA
FGF
IPD
LRRK
prion protein gene
V 180I mutation
WGS
Genetic Creutzfeldt-Jakob Disease Patients
ND
V 180I Mutation
P 102L V 180I
gCJD patients
200K
variant
2016-06-24 19:25:42
Figure
https://plos.figshare.com/articles/figure/Results_of_RT-QuIC_analysis_/3925632
<p>ThT fluorescence was measured by relative fluorescence units (rfu) with saturation occurring at 65,000 for every 42 min. The RT-QuIC responses were performed using 10<sup>−3</sup> dilution of sCJD patient with 129MM type brain homogenate (NHBX0/0001), 10<sup>−5</sup> CJD negative control brain homogenate (NHBZ0/0005), 15ul of 10<sup>−1</sup> dilution of CSF from 4 gCJD cases with V180I (the Patients nos. 1, 2, 3 and 5) and 1 sCJD case with 129MM. Each point represents the mean of 4 replicate rfu readings.</p>