Image Analysis Method. Eric A. Wright Christopher D. d’Esterre Laura B. Morrison Neil Cockburn Michael Kovacs Ting-Yim Lee 10.1371/journal.pone.0158157.g001 https://plos.figshare.com/articles/figure/Image_Analysis_Method_/3923010 <p>Infarct (pink) was identified on a PET image (top left) acquired 160-185min after ET-1 injection as pixels in the affected side ROI with signal below the infarction threshold derived from the contralateral ROI. Pixels with signal above this threshold were classified as non-infarct (yellow). The average image (top right) was used to segment out white matter. Blood vessels were identified on the BV map (bottom left) using a threshold derived from the affected side ROI (see text). Grey matter, vessel-less infarct and non-infarct ROIs were then superimposed onto the median CBF map (bottom right).</p> 2016-06-27 19:02:29 3 hours Absolute Cerebral Blood Flow Infarction Threshold 18 F-FFMZ-PET Imaging 3 hr ischemia time Cerebral Ischemia CT Perfusion blood volume maps ROC CTP 18 F-FFMZ-PET images 18 F-FFMZ-PET imaging CBF map infarction CBF thresholds 30 minutes post ET 3- Hour Ischemia Time Previous threshold-derivation studies DWI lesion reversibility CBF maps non-infarcted pixel CBF values