Relative mRNA expression of endocannabinoid signaling-related proteins in the spleen of rats exposed to alcohol during adolescence and control rats grouped by sex. Javier PavónFrancisco MarcoEva María VázquezMariam SánchezLaura RiveraPatricia GavitoAna MelaVirginia AlénFrancisco DecaraJuan SuárezJuan GinéElena López-MorenoJosé Antonio ChowenJulie Rodríguez-de-FonsecaFernando SerranoAntonia ViverosMaría Paz 2016 <p>(A) CB<sub>1</sub> mRNA levels (fold change); (B) CB<sub>2</sub> mRNA levels (fold change); (C) PPARα mRNA levels (fold change); (D) NAPE-PLD mRNA levels (fold change); (E) DGLα mRNA levels (fold change); (F) DGLβ mRNA levels (fold change); (G) FAAH mRNA levels (fold change); (H) MGL mRNA levels (fold change); and (I) FAT/CD36 mRNA levels (fold change). The bars represent means ± SEM. The data were analyzed by two-way ANOVA and significant main effects or interaction between factors was indicated as follows: (*) p<0.05 and (**) p<0.01 denote significant main effect of <i>adolescent alcohol exposure</i>; (<sup>###</sup>) p<0.001 denotes significant interaction between <i>adolescent alcohol exposure</i> and <i>sex</i>. (<sup>aaa</sup>) p<0.001 denotes significant differences compared to female control rats after <i>post hoc</i> tests; (<sup>bbb</sup>) p<0.001 denotes significant differences compared to female alcohol-exposed rats after <i>post hoc</i> tests.</p>