10.1371/journal.pone.0161228.g002 Melissa Ochoa Melissa Ochoa Charles-Henri Malbert Charles-Henri Malbert Paul Meurice Paul Meurice David Val-Laillet David Val-Laillet Recap three-dimensional brain models showing the regions of interest (ROI) activated by chronic consumption of sugar-enriched diets. Public Library of Science 2016 reward-related brain regions basal brain metabolism insulin sensitivity dorsolateral prefrontal cortex Adult Yucatan Minipigs Excessive sugar intake insulin sensitivity index 7- month diet treatment UI ISI body weight basal brain glucose metabolism 7- month intake brain sugar transporter brain activity reward-related brain areas 18 FDG PET brain imaging 2016-09-01 04:54:24 Figure https://plos.figshare.com/articles/figure/Recap_three-dimensional_brain_models_showing_the_regions_of_interest_ROI_activated_by_chronic_consumption_of_sugar-enriched_diets_/3802542 <p>3D-representations of the ROI that were significantly activated by both glucose and fructose compared to starch group (Starch < Glucose and Starch < Fructose), using the SPM8 (statistical parametric mapping) small volume correction (SVC) analysis (<i>Punc</i> < 0.001; Threshold <i>T</i> = 6.3). APFC, anterior prefrontal cortex; DLPFC, dorsolateral prefrontal cortex; OFC, orbitofrontal cortex; CAU, caudate nucleus; PUT, putamen. There was no statistical difference between glucose and fructose groups.</p>