10.1371/journal.pone.0028476.g004 Shyam Krishna Shyam Krishna Aurélie Ray Aurélie Ray Shiv K. Dubey Shiv K. Dubey Gérald Larrouy-Maumus Gérald Larrouy-Maumus Christian Chalut Christian Chalut Romain Castanier Romain Castanier Audrey Noguera Audrey Noguera Martine Gilleron Martine Gilleron Germain Puzo Germain Puzo Alain Vercellone Alain Vercellone K. Madhavan Nampoothiri K. Madhavan Nampoothiri Jérôme Nigou Jérôme Nigou Lipoglycan increased production is associated with an enhancement of innate immune signaling. Public Library of Science 2011 enhancement innate 2011-12-02 02:18:06 Figure https://plos.figshare.com/articles/figure/_Lipoglycan_increased_production_is_associated_with_an_enhancement_of_innate_immune_signaling_/378286 <p>A, B, E, F) NF-κB activation in HEK (A, E) and THP-1 (B, F) cells. C, D, G) IL-8 production by THP-1 (C, G) and human monocyte-derived dendritic (D) cells. Cells were incubated with bacteria at MOI of 1. In F and G, cells were pre-incubated for 30 min at 37°C before bacteria addition with various antibodies, anti-TLR2 and isotype controls, at a concentration of 5 µg/ml. The results are mean ± SD of triplicate wells and are representative of at least three separate experiments using independent bacterial cultures and different MOI. *, P<0.05; **, P<0.01; ***, P<0.001; ns, not significant. In A, B, C and D), P value is given <i>vs</i> pMV. n.i., not induced.</p>