Genetic Analysis with the Immunochip Platform in Behçet Disease. Identification of Residues Associated in the HLA Class I Region and New Susceptibility Loci - Fig 4 Lourdes Ortiz-Fernández Francisco-David Carmona Marco-Antonio Montes-Cano José-Raúl García-Lozano Marta Conde-Jaldón Norberto Ortego-Centeno María Jesús Castillo Gerard Espinosa Genaro Graña-Gil Juan Sánchez-Bursón María Rosa Juliá Roser Solans Ricardo Blanco Ana-Celia Barnosi-Marín Ricardo Gómez de la Torre Patricia Fanlo Mónica Rodríguez-Carballeira Luis Rodríguez-Rodríguez Teresa Camps Santos Castañeda Juan-Jose Alegre-Sancho Javier Martín María Francisca González-Escribano 10.1371/journal.pone.0161305.g004 https://plos.figshare.com/articles/figure/Genetic_Analysis_with_the_Immunochip_Platform_in_Beh_et_Disease_Identification_of_Residues_Associated_in_the_HLA_Class_I_Region_and_New_Susceptibility_Loci_-_Fig_4/3751212 <p>Ribbon representation of the HLA molecules HLA-B*5101 (A) and HLA-A*0301 (B). The independently associated amino acid positions with Behçet’s disease are highlighted in red. A mesh representation of the HIV immunodominant epitope KM1 and a proteolipid protein peptide are shown in HLA-B*5101 and HLA-A*0301, respectively, according to Protein Data Bank entries 1E27 [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0161305#pone.0161305.ref046" target="_blank">46</a>] and 2XPG [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0161305#pone.0161305.ref037" target="_blank">37</a>].</p> 2016-08-22 17:30:52 New Susceptibility Loci Behcet Immunochip platform IL 12A BD susceptibility factor association signal 130 BD cases region gene HLA marker 278 BD cases JRKL cohort analysis validation 23R