Genetic Analysis with the Immunochip Platform in Behçet Disease. Identification of Residues Associated in the HLA Class I Region and New Susceptibility Loci - Fig 4
Lourdes Ortiz-Fernández
Francisco-David Carmona
Marco-Antonio Montes-Cano
José-Raúl García-Lozano
Marta Conde-Jaldón
Norberto Ortego-Centeno
María Jesús Castillo
Gerard Espinosa
Genaro Graña-Gil
Juan Sánchez-Bursón
María Rosa Juliá
Roser Solans
Ricardo Blanco
Ana-Celia Barnosi-Marín
Ricardo Gómez de la Torre
Patricia Fanlo
Mónica Rodríguez-Carballeira
Luis Rodríguez-Rodríguez
Teresa Camps
Santos Castañeda
Juan-Jose Alegre-Sancho
Javier Martín
María Francisca González-Escribano
10.1371/journal.pone.0161305.g004
https://plos.figshare.com/articles/figure/Genetic_Analysis_with_the_Immunochip_Platform_in_Beh_et_Disease_Identification_of_Residues_Associated_in_the_HLA_Class_I_Region_and_New_Susceptibility_Loci_-_Fig_4/3751212
<p>Ribbon representation of the HLA molecules HLA-B*5101 (A) and HLA-A*0301 (B). The independently associated amino acid positions with Behçet’s disease are highlighted in red. A mesh representation of the HIV immunodominant epitope KM1 and a proteolipid protein peptide are shown in HLA-B*5101 and HLA-A*0301, respectively, according to Protein Data Bank entries 1E27 [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0161305#pone.0161305.ref046" target="_blank">46</a>] and 2XPG [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0161305#pone.0161305.ref037" target="_blank">37</a>].</p>
2016-08-22 17:30:52
New Susceptibility Loci Behcet
Immunochip platform
IL 12A
BD susceptibility factor
association
signal
130 BD cases
region
gene
HLA
marker
278 BD cases
JRKL
cohort
analysis
validation
23R