L. Puig, Kendra M. Floden, Angela Adhikari, Ramchandra Golovko, Mikhail Y. K. Combs, Colin APP, CD45, and CD68 immunoreactivity increased in the visceral (pericardial) fat from high fat versus control diet fed mice with no robust change in Aβ immunoreactivity. <p>C57BL6/J mice at 6 weeks of age and weight matched were fed, <i>ad libitum</i>, a control (5.5% fat/weight) or high fat (21.2% fat/weight) diet for 22 weeks. Visceral pericardial adipose tissue was collected, immersion fixed, sectioned, and immunostained using anti-APP, Aβ, CD45 and CD68 antibodies and antibody binding visualized using Vector VIP as the chromogen. Representative images from 12 animals per condition are shown.</p> cd68;immunoreactivity;visceral;fed;mice;robust 2013-02-20
    https://plos.figshare.com/articles/figure/_APP_CD45_and_CD68_immunoreactivity_increased_in_the_visceral_pericardial_fat_from_high_fat_versus_control_diet_fed_mice_with_no_robust_change_in_A_946_immunoreactivity_/361763
10.1371/journal.pone.0030378.g009