Up-regulation of HSG RNA induced by 231-derived exosome-like microvesicles. Chang S. Lau David T. W. Wong 10.1371/journal.pone.0033037.g002 https://plos.figshare.com/articles/figure/_Up_regulation_of_HSG_RNA_induced_by_231_derived_exosome_like_microvesicles_/335588 <p>A) Nano Ladder. (B) Basal RNA level in serum-starved HSG cells, along with 18 s and 28 s ribosomal RNA peaks. Increased total RNA levels were observed after a 12-hour treatment with 231-derived exosome-like microvesicles (Exo) compared to lysed 231-derived exosome-like microvesicles (control, Lys Exo). Transcription inhibition by actinomycin D (ActD) diminished the increase in RNA levels induced by 231-derived exosome-like microvesicles, suggesting that transcription is activated by 231-derived exosome-like microvesicles. (C) Cell count and (D) cell viability were not affected by the treatments. * <i>P</i><0.05, ** <i>P</i><0.01, and *** <i>P</i><0.001; nā€Š=ā€Š6. All experiments were independently performed a minimum of three times.</p> 2012-03-20 01:33:08 hsg rna induced 231-derived exosome-like